California Prop 65 Chemical List Update 2025: What Businesses Need to Know
The Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California’s Proposition 65, continues to evolve in response to scientific developments, litigation trends, and regulatory priorities. Designed to protect public health, Prop 65 requires businesses to provide warnings when consumers may be exposed to chemicals known to cause cancer or reproductive or developmental harm. On December 8, 2025, California made important updates to the Proposition 65 chemical list. These changes will affect businesses, consumers, and compliance strategies across multiple industries. The Challenge with Proposition 65 Proposition 65 was created to protect public health by ensuring transparency around exposure to harmful chemicals. However, its application has led to several ongoing challenges: Key Benefits of the December 8, 2025, Update Despite the challenges, the latest update reflects California’s effort to align Proposition 65 with current scientific understanding: These updates matter because they provide consumers with clearer information about harmful chemicals, allow businesses to plan for compliance deadlines, and help regulators keep the law aligned with the latest science. Effects on Businesses The December 2025 updates have direct implications for companies selling products in California: As a result, Proposition 65 warnings are expected to become more specific, helping Californians and visitors better understand which chemicals pose which risks. Compliance Impact Across the Supply Chain Manufacturers, distributors, and retailers can expect increased compliance-related activities, including: The December 8, 2025 Proposition 65 update reinforces California’s continued commitment to grounding regulatory decisions in current science. For businesses selling into California—and for consumers who rely on warning labels—the message is clear: Proposition 65 compliance is not static, and expectations continue to evolve. To reduce risk, businesses must stay informed, assess products proactively, and adapt compliance strategies early. Partnering with experienced compliance experts like ComplianceXL can help organizations navigate Prop 65 updates efficiently, reduce enforcement and litigation risks, and align compliance efforts with broader public health objectives. FAQs: 1. What is Proposition 65?Proposition 65 is a California law that requires warnings when products expose consumers to chemicals known to cause cancer or reproductive harm. 2. What chemicals were added in December 2025?N-methyl-N-formylhydrazine was added as a carcinogen, and Bisphenol S (BPS) was listed for developmental toxicity. 3. When do the new warning requirements take effect?For both chemicals, warning requirements begin on December 8, 2026. 4. Do all products need new labels immediately?No. Businesses have time to assess product formulations and update labels before the effective date. 5. Why do so many products carry Proposition 65 warnings?Because the chemical list includes hundreds of substances, many businesses apply warnings broadly to reduce litigation risk, even when actual exposure risk may be low.
All you need to know about Prop 65 2023 update
One of the biggest updates to Prop65 in 2023 is the addition of new chemicals to the list of substances that bear warnings. There are now over 1000 chemicals on the Prop 65 list. Another important update to Prop 65 in 2023 is the revised warning conditions for consumer products. Businesses that vend products in California must now give clearer and more detailed warnings about the implicit pitfalls associated with exposure to chemicals on the Prop65 list. Chemical Type of Toxicity CAS No Date Listed 1-Bromo-3-chloropropane Cancer 109-70-6 January 27, 2023 1-Butyl glycidyl ether Cancer 2426-08-6 January 27, 2023 Glycidyl methacrylate Cancer 106-91-2 January 27, 2023 1- bromo-3-chloropropane appears as a colorless liquid. undoable in water and thick than water. May be poisonous by inhalation, ingestion, or skin immersion. N- butyl glycidyl ether appears as colorless to pale unheroic liquid with a strong, slightly unwelcome odor. Flash point roughly 164 °F. thick than water. Vapors are heavier than air. Vapors may irritate the nose, throat, and respiratory tract. Ingestion or inhalation may beget central nervous system depression. Liquid contact may oppressively irritate the eyes and skin. Dragged contact with the skin may beget defatting and drying. Glycidyl methacrylate is a colorless liquid with a gooey odor. Docks on water, and it’s an enate ester attained by formal condensation of the carboxy group of methacrylic acid with the hydroxy group of glycidol. It’s an enolate ester and an epoxide. It’s functionally related to a methacrylic acid and a glycidol. How does Proposition 65 affect me? Prop 65 notices give copping translucency for Californians but may also produce unwarranted fear or agitation for those that do not understand Prop 65 easily. Although helpful, the markers do not include any details similar as the specific chemical in question, exposure situations, or any other information to clarify how the exposure may affect your well- being. In any case, every Californian has the right to see a mount 65 warning marker in needed cases, indeed if the product is manufactured or vended by a business in a different state. The proposition exists to give further power to you by allowing you to make informed opinions that work stylish for you. Talk to one of Prop 65 Compliance specialists today! ComplianceXL offers tailored compliance solutions, risk assessments, product testing and monitoring programs, training and support to stay compliant with Prop 65 regulations in California. Our goal is to protect the reputation of businesses and ensure that they fulfill their obligations.
OEHHA intends to list three new chemicals into Prop 65
The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list 1-bromo-3-chloropropane (CAS RN 109-70-6), 1-butyl glycidyl ether (CAS RN 2426-08-6), and glycidyl methacrylate (CAS RN 106-91-2) as known to the state to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Prop 65). The Notice of Intent to List (NOIL) has been issued for 1-Bromo-3-Chloropropane, 1-Butyl Glycidyl Ether, and Glycidyl Methacrylate, it means that Cal/OSHA is considering adding these chemicals to the Proposition 65 list. The NOIL serves as a notification to the public and interested parties that Cal/OSHA is considering adding these chemicals to the list, and provides an opportunity for public comment on the proposed listing. Public Comments Date: Friday, December 2, 2022 to Monday, January 9, 2023. The California Proposition 65 requires the state of California to maintain a list of chemicals known to cause cancer, birth defects, or other reproductive harm. The Labor Code Mechanism is a process by which chemicals can be added to this list based on a determination by the California Occupational Safety and Health Administration (Cal/OSHA) that they pose a significant risk of injury or illness to workers. It is important to note that Proposition 65 does not ban the use of these chemicals, but rather requires businesses to provide warnings to consumers about their potential risks. It is up to individual consumers to decide whether they want to purchase products containing these chemicals and to take steps to protect themselves from potential exposure. Be prepared for the probable chemical additions to the CA Prop 65, talk to one of our compliance specialists to learn more.
Compliance Alert! Antimony (Trivalent Compounds) to be listed in CA Prop 65
Background The state of California prohibits on contaminating drinking water with chemicals known to cause Cancer or reproductive toxicity and is called California proposition 65 officially. The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is responsible for identifying and evaluating environmental chemicals that may be harmful to human health, and for establishing health-based exposure limits for those chemicals. One of the chemicals that OEHHA is currently evaluating is antimony (trivalent compounds). Antimony (Trivalent Compounds) Antimony is a metallic element that is found naturally in the earth’s crust. It is used in a variety of industrial and commercial products, including flame retardants, plastics, and pigments. Some antimony compounds have been shown to be toxic to humans, and long-term exposure to high levels of antimony in the air, water, or soil can cause health effects. OEHHA is currently evaluating the potential health effects of antimony (trivalent compounds) as part of the process of determining whether to list the chemical as a “developmental toxicant” under the Safe Drinking Water and Toxic Enforcement Act of 1986, also known as Proposition 65. If OEHHA determines that antimony (trivalent compounds) meets the criteria for listing as a developmental toxicant, it will be added to the Proposition 65 list of chemicals known to cause birth defects or other reproductive harm. This would require manufacturers, distributors, and retailers of products containing antimony (trivalent compounds) to provide warning labels to consumers. It is important to note that the evaluation of a chemical’s potential health effects and the decision to list it as a developmental toxicant under Proposition 65 is based on scientific evidence and expert analysis, and is subject to ongoing review and revision as new information becomes available. As per law, no person in the course of doing business shall knowingly discharge or release a chemical known to the state to cause cancer or reproductive toxicity into water or onto or into land where such chemical passes or probably will pass into any source of drinking water. In the continued effort to identify such chemicals, listing or delisting of chemicals undergo the below steps: Public notice that a chemical is under consideration for listing A public comment period Review of comments received Notice of the final decision On September 30th California Environmental Protection Agency of Environmental Health Hazard Assessment (OEHHA) intends to list antimony (trivalent compounds) as known to the state to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). The public comment period started from September 30th, 2022, to October 31st 2022 and now OEHHA is reviewing the comment received before listing under prop 65 list. For more information on how California Prop 65 regulation can affect your business in the US, talk to one of our compliance specialists today!